Regional differences in neural crest morphogenesis
نویسندگان
چکیده
منابع مشابه
Temporal requirement of Hoxa2 in cranial neural crest skeletal morphogenesis.
Little is known about the spatiotemporal requirement of Hox gene patterning activity in vertebrates. In Hoxa2 mouse mutants, the hyoid skeleton is replaced by a duplicated set of mandibular and middle ear structures. Here, we show that Hoxa2 is selectively required in cranial neural crest cells (NCCs). Moreover, we used a Cre-ERT2 recombinase system to induce a temporally controlled Hoxa2 delet...
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Tetrapods have two pairs of appendages, forelimbs and hindlimbs, that develop from fixed positions along the body axis; the forelimbs from the region of the cervical/thoracic junction and hindlimbs from the lumbar/sacral junction. While the number of vertebrae in each cervical/thoracic/lumbar/sacral territory can vary greatly among different species of vertebrates, the relative position of the ...
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Cardiac and craniofacial developmental programs are intricately linked during early embryogenesis, which is also reflected by a high frequency of birth defects affecting both regions. The molecular nature of the crosstalk between mesoderm and neural crest progenitors and the involvement of endothelial cells within the cardio-craniofacial field are largely unclear. Here we show in the mouse that...
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In contrast to the classical assumption that neural crest cells are induced in chick as the neural folds elevate, recent data suggest that they are already specified during gastrulation. This prompted us to map the origin of the neural crest and dorsal neural tube in the early avian embryo. Using a combination of focal dye injections and time-lapse imaging, we find that neural crest and dorsal ...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2010
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.4.4.12890